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Invitrogen™ CEACAM3 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA596177
Description
Immunogen sequence: MGPPSASPHR ECIPWQGLLL TASLLNFWNP PTTAKLTIES MPLSVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNSLIV GYVIGTQQAT PGAAYSGRET IYTNASLLIQ NVTQNDIGFY TLQVIKSDLV NEEAT; Positive Samples: A-549, Mouse spleen; Cellular Location: Membrane, Single-pass type I membrane protein.
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Specifications
| CEACAM3 | |
| Polyclonal | |
| Unconjugated | |
| CEACAM3 | |
| carcinoembryonic antigen CGM1; Carcinoembryonic antigen gene family (CGM1); carcinoembryonic antigen gene family 4; carcinoembryonic antigen gene family member 1; Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein); carcinoembryonic antigen related cell adhesion molecule 3; carcinoembryonic antigen-related cell adhesion molecule 3; CD66d; CD66d antigen; CEA; cea12; CEACAM3; ceacam3 {ECO:0000312; Ceacam5; Cear; Cgm1; Cgm4; CGM4AA; EG384557; nonspecific cross-reacting antigen; pregnancy-specific glycoprotein 24; Psg24; RATCEAA; RATCGM4AA; RGD:2333}; W264; W282 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 1084, 384557 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.71 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P40198 | |
| CEACAM3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human CD66d/CEACAM3 (NP_0018062). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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