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Invitrogen™ CENPA Monoclonal Antibody (5A7-2E11), PE
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA545300
This item is not returnable.
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Description
1 μg/mL of MA5-45300 was sufficient for detection of CENPA in 20 μg of U2OS cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 18kDa. Recognizes Human CENP-A.
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
Specifications
| CENPA | |
| Monoclonal | |
| 1 mg/mL | |
| 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative | |
| P49450 | |
| Cenpa | |
| Synthetic peptide corresponding to a portion of human CENP-A. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot, Immunocytochemistry | |
| 5A7-2E11 | |
| PE | |
| Cenpa | |
| CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607 | |
| Mouse | |
| Protein G | |
| RUO | |
| 1058 | |
| 4°C | |
| Liquid |
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