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Ceranib 1, Tocris Bioscience™

Product Code. 18025962
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Product Code. 18025962 Supplier Tocris Bioscience Supplier No. 4448/10

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Description

Ceramidase inhibitor; antiproliferative

Ceramidase inhibitor; inhibits proliferation in SKOV3 ovarian carcinoma cells (IC50 = 3.9 μM). Induces accumulation of ceramide species and decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 328076-61-5
Molecular Formula C26H21NO3
Molecular Weight (g/mol) 395.458
InChI Key OJMCCNQNCSCAJV-RVDMUPIBSA-N
Synonym ceranib 1, 3-3-4-methoxy-phenyl-acryloyl-6-methyl-4-phenyl-1h-quinolin-2-one, 3-2e-3-4-methoxyphenyl-1-oxo-2-propen-1-yl-6-methyl-4-phenyl-2 1h-quinolinone, 3-2e-3-4-methoxyphenyl prop-2-enoyl-6-methyl-4-phenyl-1h-quinolin-2-one, 3-e-3-4-methoxyphenyl prop-2-enoyl-6-methyl-4-phenyl-1h-quinolin-2-one
PubChem CID 5761166
IUPAC Name 3-[(E)-3-(4-methoxyphenyl)prop-2-enoyl]-6-methyl-4-phenyl-1H-quinolin-2-one
SMILES CC1=CC2=C(C=C1)NC(=O)C(=C2C3=CC=CC=C3)C(=O)C=CC4=CC=C(C=C4)OC

Specifications

Quantity 10 mg
Formula Weight 395.45
Percent Purity >98%
Chemical Name or Material Ceranib 1
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