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Invitrogen™ CERKL Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5115010
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Description
Antibody detects endogenous levels of total CERKL.
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].
Specifications
| CERKL | |
| Polyclonal | |
| Unconjugated | |
| CERKL | |
| ceramide kinase like; ceramide kinase-like; ceramide kinase-like protein; CERKL; Gm1958; retinitis pigmentosa 26 (autosomal recessive); Rp26; zgc:162213 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 375298 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide | |
| Q49MI3 | |
| CERKL | |
| A synthesized peptide derived from human CERKL(Accession Q49MI3), corresponding to amino acid residues L341-S391. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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