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CFH Monoclonal Antibody (OTI5H5), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA804532
This item is not returnable.
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Description
Complement factor H1 (Complement factor H1, factor H1, CFH) is a plasma glycoprotein (139 kDa) and the secreted form of the protein is composed of 20 repetitive units of 60 amino acids, named short consensus repeats (SCR). Factor H1 is a central regulator of early alternative pathway activation by acting as a cofactor for factor I in the cleavage of C3b into iC3b. Factor H1 also competes with factor B for binding with C3b, inhibiting excessive alternative pathway activation. Complete (homozygous) factor H1 deficiency by genetic mutation has been rarely reported.Specifications
| CFH | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P08603 | |
| CFH | |
| Human recombit protein fragment corresponding to amino acids 125-346 of human CFH produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Western Blot | |
| OTI5H5 | |
| Unconjugated | |
| CFH | |
| AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 3075 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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