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CFLAR Monoclonal Antibody (OTI2H3), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA804485
This item is not returnable.
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Description
FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.Specifications
| CFLAR | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| O15519 | |
| CFLAR | |
| Human recombit protein fragment corresponding to amino acids 1-272 of human CFLAR produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI2H3 | |
| Unconjugated | |
| CFLAR | |
| CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 8837 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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