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CFLAR Mouse anti-Human, Clone: OTI2H8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Brand:  Origene Technologies CF804581

Encompass_Preferred

Product Code. 17648051

  • € 726.00 / 100µg

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This item is not returnable. View return policy

Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Specifications

Specifications

CFLAR
Monoclonal
Unconjugated
CFLAR
CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
Mouse
Affinity Chromatography
RUO
8837
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI2H8
PBS with 8% trehalose and no preservative; pH 7.3
O15519
CFLAR
Human recombit protein fragment corresponding to amino acids 1-272 of human CFLAR produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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