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Invitrogen™ CHIA Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA593057

Product Code. 16568361

  • € 528.00 / 100µL

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Description

Description

Immunogen sequence: MVSTPENRQT FITSVIKFLR QYEFDGLDFD WEYPGSRGSP PQDKHLFTVL VQEMREAFEQ EAKQINKPRL MVTAAVAAGI SNIQSGYEIP QLSQYLDYIH VMTYDLHGSW EGYTGENSPL YKYPTDTGSN AYLNVDYVMN YWKDNGAPAE KLIVGFPTYG HNFILSNPSN TGIGAPTSGA GPAGPYAKES GIWAYYEICT FLKNGATQGW DAPQEVPYAY QGNVWVGYDN IKSFDIKAQW LKHNKFGGAM VWAIDLDDFT GTFCNQGKFP LISTLKKALG LQSASCTAPA QPIEPITAAP SGSGNGSGSS SSGGSSGGSG FCAVRANGLY PVANNRNAFW HCVNGVTYQQ NCQAGLVFDT SCDCCNWA; Positive Samples: U-87MG, HepG2, Mouse stomach, Rat lung, Rat stomach; Cellular Location: Cytoplasm.

CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CHIA
Polyclonal
Unconjugated
CHIA
2200003E03Rik; acidic chitinase; acidic mammalian chitinase; AMCASE; Chia; Chia1; CHIT2; chitinase, acidic; chitinase, acidic 1; eosinophil chemotactic cytokine; lung-specific protein TSA1902; small acid mammalian chitinase; TSA1902; YNL
Rabbit
Affinity Chromatography
RUO
113901, 27159, 81600
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
0.06 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q6RY07, Q91XA9, Q9BZP6
CHIA, Chia1
Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CHIA (NP_0012449321).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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