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CHIR-98014, MedChemExpress

Product Code. 16465538
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Product Code. 16465538 Supplier Medchem Express Supplier No. HY13076

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Description

MedChemExpress CHIR-98014 is a potent, cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively; it shows less potent activities against cdc2 and erk2.

CHIR-98014 is a potent, cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively

Specifications

Chemical Name or Material CHIR-98014
CAS 252935-94-7
Color Yellow
Purity Grade Notes Research
Molecular Formula C20H17Cl2N9O2
Quantity 10 mg
Solubility Information DMSO : 12.5 mg/mL (25.70 mM; ultrasonic and warming and heat to 60°C)
SMILES ClC1=CC(Cl)=CC=C1C2=NC(NCCNC3=CC=C([N+]([O-])=O)C(N)=N3)=NC=C2N4C=CN=C4
Molecular Weight (g/mol) 486.31
Formula Weight 486.31
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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