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Invitrogen™ CHMP2B Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA592444
This item is not returnable.
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Description
Immunogen sequence: MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD; Positive Samples: MCF7, BT-474, 22Rv1, Lovo, A-549, Mouse lung, Mouse testis, Mouse kidney; Cellular Location: Cytoplasm, Late endosome membrane, Peripheral membrane protein, cytosol.
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
Specifications
| CHMP2B | |
| Polyclonal | |
| Unconjugated | |
| Chmp2b | |
| 1190006E07Rik; ALS17; CGI-84; Charged multivesicular body protein 2b; charged multivesicular body protein 2Bb; CHMP family; CHMP2.5; CHMP2B; chmp2bb; chmp2bl; chromatin modifying protein 2B; chromatin modifying protein 2B, like; chromatin modifying protein 2Bb; chromatin-modifying protein 2b; DMT1; hVps2-2; hypothetical protein LOC615954; hypothetical protein zgc:77025; RGD1306781; si:ch211-106g5.3; Vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; VPS2-2; VPS2B; zgc:77025 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 25978, 68942 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 0.22 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8BJF9, Q9UQN3 | |
| Chmp2b | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B (NP_0547622). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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