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Invitrogen™ CHMP2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA592444

Product Code. 16548261

€ 520.00 / 100µL

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Description

Immunogen sequence: MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD; Positive Samples: MCF7, BT-474, 22Rv1, Lovo, A-549, Mouse lung, Mouse testis, Mouse kidney; Cellular Location: Cytoplasm, Late endosome membrane, Peripheral membrane protein, cytosol.

CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).

Specifications

Antigen	CHMP2B
Classification	Polyclonal
Conjugate	Unconjugated
Gene	Chmp2b
Gene Alias	1190006E07Rik; ALS17; CGI-84; Charged multivesicular body protein 2b; charged multivesicular body protein 2Bb; CHMP family; CHMP2.5; CHMP2B; chmp2bb; chmp2bl; chromatin modifying protein 2B; chromatin modifying protein 2B, like; chromatin modifying protein 2Bb; chromatin-modifying protein 2b; DMT1; hVps2-2; hypothetical protein LOC615954; hypothetical protein zgc:77025; RGD1306781; si:ch211-106g5.3; Vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; VPS2-2; VPS2B; zgc:77025
Host Species	Rabbit
Purification Method	Affinity Chromatography
Regulatory Status	RUO
Gene ID (Entrez)	25978, 68942
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Western Blot
Concentration	0.22 mg/mL
Formulation	PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.	Q8BJF9, Q9UQN3
Gene Symbols	Chmp2b
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B (NP_0547622).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse
Product Type	Antibody
Isotype	IgG

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Invitrogen™ CHMP2B Polyclonal Antibody

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