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Invitrogen™ Cholera Toxin beta Polyclonal Antibody, HRP
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA173189
This item is not returnable.
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Description
The PA1-73189 antibody reacts with Cholera toxin beta subunit. PA1-73189 has been successfully used in ELISA applications. The PA1-73189 antibody was raised against purified Choleragenoid.
Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.
Specifications
| Cholera Toxin beta | |
| Polyclonal | |
| HRP | |
| CTB; CTX; VC1456 | |
| Purified Choleragenoid. | |
| 1 mL | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA | |
| 1.0 mg/mL | |
| PBS with 10mg/mL BSA and 0.002% thimerosal; pH 7.2 | |
| Rabbit | |
| Protein A | |
| RUO | |
| Bacteria | |
| Antibody | |
| IgG |
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