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Chromogranin A Antibody (CHGA/777) - Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
€ 613.00
Specifications
| Antigen | Chromogranin A |
|---|---|
| Clone | CHGA/777 |
| Concentration | 1.0 mg/mL |
| Dilution | Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready |
| Applications | Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF |
Description
Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Rat (Negative) samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
| Chromogranin A | |
| 1.0 mg/mL | |
| Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF | |
| Unconjugated | |
| Mouse | |
| Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers | |
| PBS with No Preservative | |
| 1113 | |
| Recombinant full-length human CHGA protein | |
| Primary | |
| Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| CHGA/777 | |
| Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready | |
| Monoclonal | |
| Purified | |
| RUO | |
| Human, Rat (Negative) | |
| betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I | |
| CHGA | |
| IgG1 κ | |
| Protein A or G purified | |
| Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin. |
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