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  6. Chromogranin A Antibody (CHGA/777) - Azide and BSA Free, Novus Biologicals™

Chromogranin A Antibody (CHGA/777) - Azide and BSA Free, Novus Biologicals™

Product Code. p-7105835 Shop All Bio Techne Products
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18173139 0.1 mg 0.1mg
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Product Code. 18173139 Supplier Novus Biologicals Supplier No. NBP2478480.1MG

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Description

Mouse Monoclonal Antibody

Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Rat (Negative) samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chromogranin A
Applications Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Classification Monoclonal
Clone CHGA/777
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Gene Symbols CHGA
Host Species Mouse
Immunogen Recombinant full-length human CHGA protein
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers
Primary or Secondary Primary
Gene ID (Entrez) 1113
Test Specificity Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Target Species Human, Rat (Negative)
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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