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Chromogranin A Antibody (PHE5), Alexa Fluor™ 405, Novus Biologicals™

Product Code. 18157308 Shop All Bio Techne Products
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Product Code. 18157308 Supplier Novus Biologicals Supplier No. NBP234709AF405

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Mouse Monoclonal Antibody

Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Primate, Monkey, Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Chromogranin A
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone PHE5
Conjugate Alexa Fluor 405
Dilution Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Gene Symbols CHGA
Host Species Mouse
Immunogen Human pheochromocytoma (Uniprot: P10645)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Neuronal Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 1113
Test Specificity Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Target Species Human, Primate, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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