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Invitrogen™ CIDEA Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA519907
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Description
In Western blot applications, this antibody detects a band at ~23kDa. A suggested positive control is human brain tissue lysate. PA5-19907 can be used with blocking peptide PEP-0033.
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Specifications
| CIDEA | |
| Polyclonal | |
| Unconjugated | |
| CIDEA | |
| AW212747; cell death activator CIDE-A; Cell death-inducing DFFA-like effector A; cell death-inducing DNA fragmentation factor, alpha subunit-like effector A; cide a; Cidea; CIDE-A | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1149 | |
| Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| O60543 | |
| CIDEA | |
| A peptide corresponding to amino acids 200 to 217 of human CIDE-A. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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