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Invitrogen™ Claudin 6 Monoclonal Antibody (AFB17981)
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Product Code. 17256673 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17256673 100 μL 100µL
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Product Code. 17256673 Supplier Invitrogen™ Supplier No. MA537461

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Description

Mouse Monoclonal Antibody

Antibody detects endogenous levels of total CLDN6.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 6
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone AFB17981
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene CLDN6
Gene Accession No. P56747
Gene Alias AL024037; claudin 6; Claudin6; claudin-6; CLD6; CLDN6; Skullin; tight junction molecule claudin 6; UNQ757/PRO1488
Gene Symbols CLDN6
Host Species Mouse
Immunogen A synthesized peptide derived from human CLDN6, corresponding to amino acid residues L88-W138.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9074
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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