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CLEC10A/CD301 Antibody (ER-MP23), DyLight 550, Novus Biologicals™

Rat Monoclonal Antibody

Brand:  Novus Biologicals NB100-64874R

Product Code. 18036704

  • € 595.00 / 125µL

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Description

Description

CLEC10A/CD301 Monoclonal specifically detects CLEC10A/CD301 in Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CLEC10A/CD301
Monoclonal
DyLight 550
50 mM sodium borate with 0.05% sodium azide
CLEC10A
Balb/c macrophage precursor cell hybrids
Immunology
10462
Mouse
IgG2a
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
ER-MP23
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
CD301 antigen, CD301C-type lectin domain family 10 member A, CLECSF13, CLECSF14macrophage C-type lectin, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 14 (macrophage-derived), C-type lectin domain family 10, member A, C-type lectin superfamily member 14, HML2, HMLC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 13 (macrophage-derived), Macrophage lectin 2, macrophage lectin 2 (calcium dependent), MGL
Rat
0.125 mL
Primary
NB100-64874 recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated. Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.
Store at 4°C in the dark.
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