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Invitrogen™ CLIP1 Polyclonal Antibody
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Product Code. 16526791
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Quantity:
100 μL
Unit Size:
100µL
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16526791 100 μL 100µL
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Product Code. 16526791 Supplier Invitrogen™ Supplier No. PA588590

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SALLTEKDAE LEKLRNEVTV LRGENASAKS LHSVVQTLES DKVKLELKVK NLELQLKENK RQLSSSSGNT DTQADEDERA QESQIDFLNS VIVDLQRKNQ DLKMKVEMMS EAALNGNGDD LNNYDSDDQE KQSKKKPRLF CDICDCFDLH DTEDCPTQAQ MSEDPPHSTH HGSRGEERPY CEICEMFGHW ATNCNDDETF; Positive Samples: U-87MG, Mouse heart; Cellular Location: Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Peripheral membrane protein, cytoskeleton, ruffle.

CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLIP1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CLIP1
Gene Accession No. P30622, Q922J3, Q9JK25
Gene Alias 1110007I12Rik; 4631429H07Rik; AV017631; C81039; CAP-Gly domain containing linker protein 1; CAP-Gly domain-containing linker protein 1; CLIP; Clip 170; Clip1; CLIP170; CLIP-170; Clip50; Cyln1; cytoplasmic linker protein 1; Cytoplasmic linker protein 170; Cytoplasmic linker protein 170 alpha-2; cytoplasmic linker protein 50; cytoplasmic linker protein CLIP-170; Kiaa4046; MGC131604; mKIAA4046; Reed-Steinberg cell-espressed intermediate filament-associated protein; Reed-Sternberg intermediate filament-associated protein; Restin; restin (Reed-Steinberg cell-espressed intermediate filament-associated protein); restin (Reed-Steinberg cell-expressed intermediate filament-associated protein); Rsn
Gene Symbols CLIP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1228-1427 of human CLIP1 (NP_0029471).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56430, 6249, 65201
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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