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Invitrogen™ CLN5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA588837

Product Code. 16556931

€ 520.00 / 100µL

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Description

Immunogen sequence: IPSRRHWPVP YKRFDFRPKP DPYCQAKYTF CPTGSPIPVM EGDDDIEVFR LQAPVWEFKY GDLLGHLKIM HDAIGFRSTL TGKNYTMEWY ELFQLGNCTF PHLRPEMDAP FWCNQGAACF FEGIDDVHWK ENGTLVQVAT ISGNMFNQMA KWVKQDNETG IYYETWNVKA SPEKGAETWF DSYDCSKFVL RTFNKLAEFG AEFKNIETNY TRIFLYSGEP TYLGNETSVF GPTGNKTLGL AIKRFYYPFK PHLPTKEFLL SLLQIFDAVI VHKQFYLFYN FEYWFLPMKF PFIKITYEEI PLPIRNKTLS GL; Positive Samples: Mouse heart, Rat heart; Cellular Location: Lysosome.

This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008].

Specifications

Antigen	CLN5
Classification	Polyclonal
Conjugate	Unconjugated
Gene	CLN5
Gene Alias	A730075N08Rik; ceroid-lipofuscinosis; Ceroid-lipofuscinosis neuronal protein 5; ceroid-lipofuscinosis neuronal protein 5 homolog; Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Ceroid-lipofuscinosis neuronal protein 5, secreted form; ceroid-lipofuscinosis, neuronal 5; CLN5; NCL; Protein CLN5
Host Species	Rabbit
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	1203, 211286, 306128
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration	2.8 mg/mL
Formulation	PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.	O75503, Q3UMW8
Gene Symbols	CLN5
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 47-358 of human CLN5 (NP_006484.2).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse, Rat
Product Type	Antibody
Isotype	IgG

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Invitrogen™ CLN5 Polyclonal Antibody

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