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Invitrogen™ CLNS1A Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5109555
Description
Immunogen sequence: MSFLKSFPPP GPAEGLLRQQ PDTEAVLNGK GLGTGTLYIA ESRLSWLDGS GLGFSLEYPT ISLHALSRDR SDCLGEHLYV MVNAKFEEES KEPVADEEEE DSDDDVEPIT EFRFVPSDKS ALEAMFTAMC ECQALHPDPE DEDSDDYDGE EYDVEAHEQG QGDIPTFYTY EEGLSHLTAE GQATLERLEG MLSQSVSSQY NMAGVRTEDS IRDYEDGMEV DTTPTVAGQF EDADVDH.
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
Specifications
| CLNS1A | |
| Polyclonal | |
| Unconjugated | |
| CLNS1A | |
| 2610036D06Rik; 2610100O04Rik; ARPC1A; chloride channel; chloride channel current inducer; chloride channel regulator; chloride channel regulatory protein; chloride channel, nucleotide sensitive 1A; chloride channel, nucleotide-sensitive, 1A; chloride conductance regulatory protein ICln; Chloride ion current inducer protein; chloride nucleotide-sensitive channel 1A; ClCI; Clcni; Clns 1a; CLNS1A; CLNS1B; I(Cln); icln; icln protein; methylosome subunit pICln; pIcIn; pICln; Rcl1; Reticulocyte pICln; reticulocyte protein ICln; SOP2L; SOP2-like protein; swelling dependent chloride channel; swelling-induced chloride conductance regulatory protein; swelling-induced chloride conductance regulatory protein pIcIn | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 1207, 12729, 65160 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 0.41 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| P54105, Q04753, Q61189 | |
| CLNS1A | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human CLNS1A (NP_001284.1). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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