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Invitrogen™ CMKLR1 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA533437

Product Code. 15304591

  • € 516.00 / 50µg

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Description

Description

CMKLR1 Polyclonal Antibody for IHC (P)

Chemokine-like receptor 1 (CMKLR1) is a receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. CMKLR1 positively regulates adipogenesis and adipocyte metabolism and acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CMKLR1
Polyclonal
Unconjugated
CMKLR1
chemerin chemokine-like receptor 1; chemerin receptor; CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; CHEMR23; CMKLR1; Dez; Gpcr27; G-protein coupled chemoattractant-like receptor; G-protein coupled receptor 27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; mcmklr1; orphan G-protein coupled receptor, Dez; resolvin E1 receptor; RVER1
Rabbit
Antigen affinity chromatography
RUO
100355497, 1240, 486321
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.1% sodium azide
Q99788
CMKLR1
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human CMKLR1.
50 μg
Primary
Human, Canine, Rabbit, Monkey
Antibody
IgG
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