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Invitrogen™ CNGB3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5103768
This item is not returnable.
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Description
Antibody detects endogenous levels of total CNGB3.
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Specifications
| CNGB3 | |
| Polyclonal | |
| Unconjugated | |
| CNGB3 | |
| ACHM1; cng channel; CNG channel beta-3; CNGB3; cone photoreceptor cGMP-gated cation channel beta-subunit; Cone photoreceptor cGMP-gated channel subunit beta; cyclic nucleotide gated channel beta 3; cyclic nucleotide-gated cation channel beta-3; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 30952, 54714 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q9JJZ9, Q9NQW8 | |
| CNGB3 | |
| A synthesized peptide derived from human CNGB3(Accession Q9NQW8), corresponding to amino acid residues N90-R140. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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