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Invitrogen™ CNOT3 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100231

Product Code. 16666714

  • € 494.00 / 100µL

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Description

Description

Antibody detects endogenous levels of total CNOT3.

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CNOT3
Polyclonal
Unconjugated
CNOT3
A930039N10Rik; CCR4-associated factor 3; CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex, subunit 3; CNOT3; KIAA0691; LENG2; Leukocyte receptor cluster member 2; Not3; NOT3 (negative regulator of transcription 3, yeast) homolog; NOT3H
Rabbit
Affinity chromatography
RUO
232791, 308311, 4849
-20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O75175, Q8K0V4
CNOT3
A synthesized peptide derived from human CNOT3(Accession O75175), corresponding to amino acid residues S258-V308.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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