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Invitrogen™ CNTFR Polyclonal Antibody
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Product Code. 16609114
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Quantity:
100 μL
Unit Size:
100µL
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16609114 100 μL 100µL
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Product Code. 16609114 Supplier Invitrogen™ Supplier No. PA5102646

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CNTFR.

This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNTFR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cntfr
Gene Accession No. O88507, P26992, Q08406
Gene Alias ciliary neurotrophic factor receptor; ciliary neurotrophic factor receptor alpha; ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; Cntfr; CNTFR alpha; CNTFRALPHA; CNTFR-alpha; MGC1774
Gene Symbols Cntfr
Host Species Rabbit
Immunogen A synthesized peptide derived from human CNTFR(Accession P26992), corresponding to amino acid residues L97-H147.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1271, 12804, 313173
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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