missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Cofilin Recombinant Rabbit Monoclonal Antibody (4M1Z9)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA542790
This item is not returnable.
View return policy
Description
Positive test controls include: HeLa, 293T, MCF7, NIH/3T3, C6, Mouse lung, Mouse thymus, Rat brain. The target is usually found in the following locations: Cell projection, Cytoplasm, Cytoplasmic side, Nucleus matrix, Peripheral membrane protein, cytoskeleton, lamellipodium membrane, ruffle membrane. Immunogen sequence: MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV GQTVDDPYAT FVKMLPDKDC RYALYDATYE TKESKKEDLV.
Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
Specifications
| Cofilin | |
| Recombinant Monoclonal | |
| 1.5 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P18760, P23528, P45592 | |
| CFL1 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cofilin (P23528). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 4M1Z9 | |
| Unconjugated | |
| CFL1 | |
| 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 1072, 12631, 29271 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction