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Invitrogen™ COMP Monoclonal Antibody (4H6G10D2)

Description
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human COMP/THBS5.
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Specifications
Specifications
| Antigen | COMP |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | 4H6G10D2 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | COMP |
| Gene Accession No. | P49747 |
| Gene Alias | Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); Comp; EDM1; EPD1; MED; MGC131819; MGC149768; PSACH; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); putative cartilage oligomeric matrix protein; THBS5; Thrombospondin5; Thrombospondin-5; TSP 5; TSP5 |
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