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  6. COMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

COMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7205552 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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Product Code. Quantity unitSize
16823564 20 μL 20µL
16813564 150 μL 150µL
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Product Code. 16823564 Supplier Proteintech Supplier No. 147541AP20UL

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Description

Rabbit Polyclonal Antibody

COMT (Catechol-O-methyltransferase) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Specifications

Antigen COMT
Applications Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene COMT
Gene Accession No. O88587, P21964, P22734
Gene Alias catechol O methyltransferase, COMT
Gene Symbols COMT
Host Species Rabbit
Immunogen COMT Fusion Protein Ag6502
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12846, 1312, 24267
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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