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Invitrogen™ CORIN Polyclonal Antibody
Description
Immunogen sequence: MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS; Positive Samples: Hela, HT-1080, Mouse heart, Mouse brain, Rat heart, Rat brain; Cellular Location: Cell membrane, Single-pass type II membrane protein, Single-pass type II membrane protein.
CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
Specifications
Specifications
| Antigen | CORIN |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.99 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | CORIN |
| Gene Accession No. | Q80YN4, Q9Y5Q5, Q9Z319 |
| Gene Alias | ATC2; Atrial natriuretic peptide-converting enzyme; Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; AV273130; Corin; corin, serine peptidase; CRN; EC 3.4.21; Heart-specific serine proteinase ATC2; low density lipoprotein receptor-related protein 4; low density lipoprotein-related protein 4; Lrp4; MGC119742; PEE5; pro-ANP-convertase; pro-ANP-converting enzyme; PRSC; serine peptidase; serine protease; TMPRSS10; Transmembrane protease serine 10 |
| Gene Symbols | CORIN |
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