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Invitrogen™ Cripto Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA518951
This item is not returnable.
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Description
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
Specifications
| Cripto | |
| Polyclonal | |
| Unconjugated | |
| TDGF1 | |
| CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR) | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 6997 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P13385 | |
| TDGF1 | |
| Synthetic peptide sequence (YGRNCEHDVRKEN) corresponding to the internal amino acids of TDGF1 (aa 102-115). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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