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Invitrogen™ CSB Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA579218
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Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human A431 whole cell, human Siha whole cell.
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
Specifications
| CSB | |
| Polyclonal | |
| Unconjugated | |
| ERCC6 | |
| 4732403I04; ARMD5; ATP-dependent helicase ERCC6; C130058G22Rik; Chimeric CSB-PGBD3 protein; Chimeric ERCC6-PGBD3 protein; CKN2; Cockayne syndrome group B protein; cockayne syndrome protein CSB; COFS; COFS1; CS group B correcting; CSB; DNA excision repair protein ERCC-6; DNA excision repair protein ERCC-6; ERCC6-PGBD3 fusion protein; ERCC excision repair 6, chromatin remodeling factor; ERCC6; ERCC6-PGBD3 fusion protein (isoform 1); excision repair cross-complementation group 6; excision repair cross-complementing rodent repair deficiency, complementation group 6; POF11; RAD26; UVSS1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2074 | |
| -20°C | |
| Lyophilized |
| Western Blot | |
| 500 μg/mL | |
| PBS with 5mg BSA and 0.05mg sodium azide | |
| Q03468 | |
| ERCC6 | |
| A synthetic peptide corresponding to a sequence at the N-terminus of human CSB (160-205aa QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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