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CSE1L Monoclonal Antibody (OTI2C5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Brand:  Origene Technologies TA812194

Encompass_Preferred

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Product Code. 17586524

  • € 540.87 / 100µL

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This item is not returnable. View return policy

Description

Description

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
Specifications

Specifications

CSE1L
Monoclonal
Unconjugated
CSE1L
CAS, CSE1, XPO2
Mouse
Affinity Chromatography
RUO
1434
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
OTI2C5
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P55060
CSE1L
Human recombit protein fragment corresponding to amino acids 1-300 of human CSE1L produced in E.coli.
100 μL
Primary
Human
Antibody
IgG2b
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