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CTNNB1 (phospho S715) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Product Code. 16254340
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Quantity:
100 μL
Unit Size:
100µL
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16254340 100 μL 100µL
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Product Code. 16254340 Supplier Abnova Supplier No. PAB29626.100uL

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CTNNB1.

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]

Specifications

Antigen CTNNB1 (phospho S715)
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CTNNB1.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias CTNNB/DKFZp686D02253/FLJ25606/FLJ37923
Gene Symbols CTNNB1
Host Species Rabbit
Immunogen A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S715 of human CTNNB1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1499
Test Specificity CTNNB1 (phospho S715) polyclonal antibody detects endogenous level of CTNNB1 only when phosphorylated at serine 715.
Target Species Human, Mouse, Rabbit
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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