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Invitrogen™ CXCL10 Monoclonal Antibody (4D5)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA180897
This item is not returnable.
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Description
Mouse anti Human IP-10 antibody, clone 4D5 recognizes human C-X-C motif chemokine 10, also known as IP-10, Small-inducible cytokine B10 or CXCL10. IP-10 is a 98 amino acid approximately 10kDa CxC chemokine induced by interferon gamma (P02778).
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
Specifications
| CXCL10 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| P02778 | |
| CXCL10 | |
| Recombinant human IP-10. | |
| 500 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| ELISA, Western Blot, Immunocytochemistry | |
| 4D5 | |
| Unconjugated | |
| CXCL10 | |
| 10 kDa interferon gamma-induced protein; 10 kDa interferon-gamma induced protein precursor; C Cmotif chemokine; C X C motif chemokine; C7; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; chemokine C-X-C motif ligand 10; chemokine CXC-like protein; Crg2; CRG-2; CXC; CXC chemokine; CXC motif chemokine; C-X-C motif chemokine 10; C-X-C motif chemokine 10-like protein; C-X-C motif chemokine ligand 10; CXCL; CXCL10; CXCL10(1-73); gamma interferon inducible protein 10; gamma IP10; gamma-IP10; gIP-10; H-IP-10; IFI10; Inp10; interferon activated gene 10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; interferon-gamma-inducible protein 10; interferon-gamma-inducible protein-10; interferon-inducible cytokine IP-10; interferon-inducible protein 10; IP10; IP-10; M-IP-10; Mob1; mob-1; protein 10 from interferon (gamma)-induced cell line; protein Mob-1; Scyb10; similar to Small inducible cytokine B10 precursor (CXCL10) (10 kDa interferon-gamma induced protein) (Gamma-IP10) (IP-10); small inducible cytokine B subfamily (Cys-X-Cys) member 10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small inducible cytokine subfamily B (Cys-X-Cys), member 10; small-inducible cytokine B10 | |
| Mouse | |
| Protein A | |
| RUO | |
| 3627 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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