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Invitrogen™ CXCL3 Polyclonal Antibody

Goat Polyclonal Antibody
Brand: Invitrogen™ PA547704
Description
In direct ELISAs, greater than 50% cross-reactivity with recombinant rat (rr) CINC-1, rrCINC-2 beta, and rrCINC-3 is observed, less than 25% cross-reactivity with recombinant mouse (rm) KC, rmMIP-2, recombinant human (rh) GRO alpha, rhGRO beta, and rhGRO gamma is observed, and less than 10% cross-reactivity with rhIL-8 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
CXCL3 may play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils.
Specifications
| CXCL3 | |
| Polyclonal | |
| Unconjugated | |
| Cxcl3 | |
| C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 3; Cinc2; CINC-2; CINC-2b; CXC; CXC motif chemokine; C-X-C motif chemokine 3; C-X-C motif chemokine ligand 3; CXCL; Cxcl3; cytokine-induced neutrophil chemoattractant 2; cytokine-induced neutrophil chemoattractant-2; Dcip1; Dendritic cell inflammatory protein 1; Gm1960; gro gamma; GRO3; GRO3 oncogene; GROG; GRO-gamma; GRO-gamma(1-73); GRO-gamma(5-73); Growth-regulated protein gamma; macrophage inflammatory protein 2-alpha/beta; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2-alpha/beta; MIP2B; MIP-2b; MIP2-beta; SCYB3 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 171551 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with No Preservative | |
| Q10746 | |
| Cxcl3 | |
| E. coli-derived recombinant rat CXCL3/CINC-2 alpha/beta Arg33-Ser100. | |
| 100 μg | |
| Primary | |
| Rat | |
| Antibody | |
| IgG |
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