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Description
Immunogen sequence: SGLLVYQGKG KFAIRPDKKS NPIIRTVKSV GMIAGGTGIT PMLQVIRAIM KDPDDHTVCH LLFANQTEKD ILLRPELEEL RNKHSARFKL WYTLDRAPEA WDYGQGFVNE EMIRDHLPPP EEEPLVLMCG PPPMIQYACL PNLDH Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction.
Specifications
Specifications
| Antigen | CYB5R3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CYB5R3 |
| Gene Accession No. | P00387 |
| Gene Alias | 0610016L08Rik; 2500002N19Rik; B5R; C5BR; C85115; CB5R; Cyb5r3; cytochrome b5 reductase 3; DIA1; Dia-1; Diaphorase (NADH) (cytochrome b-5 reductase); diaphorase 1; diaphorase 1 (NADH); Diaphorase1; diaphorase-1; LOC100524254; LOW QUALITY PROTEIN: NADH-cytochrome b5 reductase 3-like; mutant NADH-cytochrome b5 reductase; Nadhcb5; NADH-cytochrome b5 reductase 3; NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form; NADH-cytochrome b5 reductase 3-like; RNNADHCB5; WU:AL591952.1-001; WU:AL591952.1-002; WU:AL591952.1-003; WU:Cyb5r3 |
| Gene Symbols | CYB5R3 |
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Product Title
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