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  6. Invitrogen™ USP5 Recombinant Rabbit Monoclonal Antibody (24GB2480)

Invitrogen™ USP5 Recombinant Rabbit Monoclonal Antibody (24GB2480)
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Product Code. 30276065
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30276065 100 μL 100µL
30276045 20 μL 20µL
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Product Code. 30276065 Supplier Invitrogen™ Supplier No. MA557820

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Description

Rabbit Recombinant Monoclonal Antibody

USP5 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

USP5 (ubiquitin carboxyl-terminal hydrolase 5) cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. It is involved in unanchored Lys-48-linked polyubiquitin disassembly, and also binds linear and Lys-63 linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP5
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 24GB2480
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene USP5
Gene Accession No. P45974, P56399
Gene Alias AA407472; deubiquitinating enzyme 5; EGK_03293; Isopeptidase T; Isot; ISOT-1; testicular tissue protein Li 218; ubiquitin carboxy terminal hydrolase T; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin isopeptidase T; ubiquitin specific peptidase 5; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5; ubiquitin specific protease 5 (isopeptidase T); ubiquitin thioesterase 5; ubiquitin thiolesterase 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ubiquitin-specific-processing protease 5; Ucht; Usp5
Gene Symbols USP5
Host Species Rabbit
Immunogen A synthesized peptide derived from human USP5 (aa 770-835).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22225, 297593, 8078
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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