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Invitrogen™ CYP17A1 Recombinant Rabbit Monoclonal Antibody (5D2H1)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535632
This item is not returnable.
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Description
Immunogen sequence: TLDIASNNRK GIAFADSGAH WQLHRRLAMA TFALFKDGDQ KLEKIICQEI STLCDMLATH NGQSIDISFP VFVAVTNVIS LICFNTSYKN GDPELNVIQN YNEGIIDNLS KDSLVDLVPW.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Specifications
| CYP17A1 | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P05093, P27786 | |
| CYP17A1 | |
| Recombinant protein (or fragment). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| ELISA, Western Blot, Immunocytochemistry | |
| 5D2H1 | |
| Unconjugated | |
| CYP17A1 | |
| 17a-hydroxylase; 17-alpha-hydroxyprogesterone aldolase; CPT7; Cyp17; Cyp17a1; CYPXVII; cytochrome P450 17A1; cytochrome P450 family 17 subfamily A member 1; cytochrome p450 XVIIA1; cytochrome P450, 17; cytochrome P450, 17a1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily 17; Cytochrome P450, subfamily XVII; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; Cytochrome P450c17; cytochrome P450-C17; HGNC:2593; P45017alpha; p450c17; P450-C17; S17AH; steroid 17-alpha hydroxylase; steroid 17-alpha-hydroxylase/17,20 lyase; Steroid 17-alpha-monooxygenase | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 13074, 1586 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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