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CYP1A2 Monoclonal Antibody (OTI2E9), TrueMAB™, OriGene

Product Code. 17573561
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17573561 100 μL 100µL
17593561 30 μL 30µL
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Product Code. 17573561 Supplier Origene Technologies Supplier No. TA501197

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Description

Mouse Monoclonal Antibody

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme′s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.

Specifications

Antigen CYP1A2
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI2E9
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene CYP1A2
Gene Accession No. P05177
Gene Alias CP12, CYPIA2, P3-450, P450(PA)
Gene Symbols CYP1A2
Host Species Mouse
Immunogen Full length human recombit protein of human CYP1A2 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1544
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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