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Invitrogen™ CYP3A4/CYP3A5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5101318
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Description
Antibody detects endogenous levels of total Cytochrome P450 3A4/5.
CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
Specifications
| CYP3A4/CYP3A5 | |
| Polyclonal | |
| Unconjugated | |
| CYP3A4 | |
| 1,8-cineole 2-exo-monooxygenase; albendazole monooxygenase; Albendazole monooxygenase (sulfoxide-forming); Albendazole sulfoxidase; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP33; CP34; CP35; CYP3A; CYP3A28; CYP3A3; CYP3A4; CYP3A5; CYPIIIA28; CYPIIIA3; CYPIIIA4; CYPIIIA5; cytochrome P450; cytochrome P450 3A28; cytochrome P450 3A3; Cytochrome P450 3A4; cytochrome P450 3A5; cytochrome P450 family 3 subfamily A member 4; cytochrome P450 family 3 subfamily A member 5; cytochrome P450 HLp; cytochrome P450 HLp2; cytochrome P450 NF-25; cytochrome P450, family 3, subfamily A, polypeptide 4; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450, subfamily IIIA, polypeptide 4; cytochrome P450-PCN1; Cytochrome P450-PCN3; flavoprotein-linked monooxygenase; glucocorticoid-inducible P450; HLP; HLp2; microsomal monooxygenase; NF-25; Nifedipine oxidase; P450C3; P450-III, steroid inducible; P450PCN1; P450PCN3; P450-PCN3; PCN3; Quinine 3-monooxygenase; taurochenodeoxycholate 6-alpha-hydroxylase; Unknown (protein for MGC:127840); xenobiotic monooxygenase | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 1576, 1577 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P08684, P20815 | |
| CYP3A4, CYP3A5 | |
| A synthesized peptide derived from human CYP3A4(Accession P08684), corresponding to amino acid residues H267-I317. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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