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Invitrogen™ CYP4Z1/CYP4Z2P Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599832

Product Code. 16684075

  • € 491.00 / 100µL

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Description

Description

Antibody detects endogenous levels of total Cytochrome P450 4Z1/2.

The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CYP4Z1/CYP4Z2P
Polyclonal
Unconjugated
CYP4Z1
CYP4A20; CYP4Z1; CYP4Z1/2; CYP4Z2P; CYPIVZ1; cytochrome P450 4Z1; cytochrome P450 family 4 subfamily Z member 1; cytochrome P450 family 4 subfamily Z member 2, pseudogene; cytochrome P450, family 4, subfamily Z, polypeptide 1; P450 4Z1/2; UNQ3060/PRO9882
Rabbit
Affinity chromatography
RUO
163720, 199974
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q86W10, Q8N1L4
CYP4Z1, CYP4Z2P
A synthesized peptide derived from human CYP4Z1(Accession Q86W10), corresponding to amino acid residues S240-S290.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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