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Invitrogen™ CYR61 Polyclonal Antibody, DyLight™ 650
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA522763

Product Code. 13217208

  • € 520.00 / 100µL

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Description

Description

This antibody is predicted to react with rat and mouse based on 88% sequence homology.

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CYR61
Polyclonal
DyLight 650
CCN1
3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Rabbit
Antigen affinity chromatography
RUO
100339657, 16007, 3491
4°C, store in dark
Liquid
Immunohistochemistry (Paraffin), Neutralization, Western Blot, Immunocytochemistry
0.58 mg/mL
50mM sodium borate with 0.05% sodium azide
O00622, P18406
CCN1
A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250).
100 μL
Primary
Human, Mouse, Rabbit
Antibody
IgG
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