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Invitrogen™ Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody (SR45-06)
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Product Code. 16345414
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Quantity:
100 μL
Unit Size:
100µL
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16345414 100 μL 100µL
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Product Code. 16345414 Supplier Invitrogen™ Supplier No. MA531986

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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
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Specifications

Antigen Cytokeratin 17
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot, Western Blot
Classification Recombinant Monoclonal
Clone SR45-06
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene KRT17
Gene Accession No. Q04695, Q6IFU8, Q9QWL7
Gene Alias 39.1; CK17; CK-17; cytokeratin-17; hard keratin; K17; Ka17; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 17; Keratin-17; Krt1-17; Krt17; krt17 {ECO:0000250; PC; PC2; PCHC1; Type I keratin Ka17; UniProtKB:Q04695}
Gene Symbols KRT17
Host Species Rabbit
Immunogen Synthetic peptide within Human Cytokeratin 17 aa 1-50.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16667, 287702, 3872
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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