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Danoprevir, MedChemExpress

Product Code. p-200101730
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Quantity:
2 mg
5 mg
10 mg
50 mg
Unit Size:
10mg
2mg
50mg
5mg
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Product Code. 16493728

Brand: Medchem Express HY10238

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Description

MedChemExpress Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM). Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 μM.

Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM). Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 μM.

Specifications

Chemical Name or Material Danoprevir
CAS 850876-88-9
Color White
Purity Grade Notes Research
Molecular Formula C35H46FN5O9S
Quantity 10 mg
Synonym ITMN-191 R7227 RO5190591 RG7227
Solubility Information DMSO : ≥ 100 mg/mL (136.64 mM)
SMILES O=S(NC([C@@]1(NC([C@]2([H])C[C@@H](OC(N3CC4=C(C3)C=CC=C4F)=O)CN2C5=O)=O)C[C@]1(/C=C/CCCCC[C@@H]5NC(OC(C)(C)C)=O)[H])=O)(C6CC6)=O
Molecular Weight (g/mol) 731.83
Formula Weight 731.83
Percent Purity 95.65%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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