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Invitrogen™ DAPK1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA517055
This item is not returnable.
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Description
It is not recommended to aliquot this antibody.
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
Specifications
| DAPK1 | |
| Polyclonal | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
| P53355, Q80YE7 | |
| DAPK1 | |
| Synthetic peptide corresponding to residues surrounding Gly903 of human DAPK1. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Monkey | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| DAPK1 | |
| D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 1612, 306722, 69635 | |
| -20°C | |
| Liquid |
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