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Invitrogen™ DAPK1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583910

Product Code. 16340865

  • € 566.00 / 100µL

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Description

Description

Immunogen sequence: HKVQVNLCRW IHQQSTEGDA DIRLWVNGCK LANRGAELLV LLVNHGQGIE VQVRGLETEK IKCCLLLDSV CSTIENVMAT TLPGLLTVKH YLSPQQLREH HEPVMIYQPR DFFRAQTLKE TSLTNTMGGY KESFSSIMCF GCHD Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 94%.

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DAPK1
Polyclonal
Unconjugated
DAPK1
D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Rabbit
Antigen affinity chromatography
RUO
1612
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.05 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P53355
DAPK1
Recombinant protein corresponding to Human DAPK1. Recombinant protein control fragment (Product #RP-103024).
100 μL
Primary
Human
Antibody
IgG
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