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Darovasertib, MedChemExpress

Product Code. 16474646
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Product Code. 16474646

Brand: Medchem Express HY101569

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Description

MedChemExpress Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research.

Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research.

Specifications

Chemical Name or Material Darovasertib
CAS 1874276-76-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H23F3N8O
Quantity 100 mg
Synonym LXS196 IDE196
Solubility Information DMSO : 25 mg/mL (52.91 mM; Need ultrasonic)
SMILES NC1=C(C(NC2=C(N3CCC(C)(N)CC3)C=CC=N2)=O)N=C(C4=NC=CC=C4C(F)(F)F)C=N1
Molecular Weight (g/mol) 472.47
Formula Weight 472.47
Percent Purity 99.12%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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