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DBR1 Mouse anti-Human, CoraLite 488, Clone: 3B5A7, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech CL488-66951-100UL

Product Code. 17274716

  • € 450.00 / 100µL

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This item is not returnable. View return policy

Description

Description

DBR1(Lariat debranching enzyme) hydrolyzes 2-prime-to-5-prime branched phosphodiester bonds at the branch point of excised lariat intron RNA and converts them into linear molecules. DBR1 belongs to the lariat debranching enzyme family. Inhibiton of Dbr1 can suppress TDP-43 toxicity in primary neurons, suggesting that Dbr1 could be a potential therapeutic target for ALS and related TDP-43 proteinopathies (PMID: 23104007). This protein has 2 isoforms produced by alternative splicing.

Specifications

Specifications

DBR1
Monoclonal
1000 μg/mL
Mouse
Primary
Human, Mouse
IgG2b
Immunofluorescence
3B5A7
CoraLite 488
100 μL
51163
Liquid
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