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Invitrogen™ DCK Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA527787
This item is not returnable.
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Description
Recommended positive controls: 293T, A431, HeLa, HepG2, A549, H1299, PC-12, Rat2, DCK-transfected 293T. Predicted reactivity: Mouse (93%), Rat (92%), Chicken (82%), Rhesus Monkey (96%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Specifications
| DCK | |
| Polyclonal | |
| Unconjugated | |
| DCK | |
| DCK; Deoxycytidine kinase; deoxynucleoside kinase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 13178, 1633, 79127 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 1.41 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P27707, P43346, P48769 | |
| DCK | |
| Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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