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Description
Immunogen sequence: VDADFELHNF RALCELESGI PAAESQIVYA ERPLTDNHRS LASYGL Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1.
Specifications
Specifications
| Antigen | DDI2 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | DDI2 |
| Gene Accession No. | Q5TDH0 |
| Gene Alias | 1110056G13Rik; 1700027M01Rik; 9130022E05Rik; AI604911; AU040698; DDI1, DNA-damage inducible 1, homolog 2; Ddi2; DNA damage inducible 1 homolog 2; DNA-damage inducible 1 homolog 2; DNA-damage inducible protein 2; DNA-damage inducible protein 2 (DDI2); protein DDI1 homolog 2; RP4-680D5.5 |
| Gene Symbols | DDI2 |
| Show More |
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