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Invitrogen™ DDR2 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5111656

Product Code. 17149573

  • € 620.00 / 100µL

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Description

Description

Immunogen sequence: FDRIRNFTTM KVHCNNMFAK GVKIFKEVQC YFRSEASEWE PNAISFPLVL DDVNPSARFV TVPLHHRMAS AIKCQ Highest antigen sequence indentity to the following orthologs: Rat - 93%, Mouse - 96%.

DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited by Gleevec. DDR2 required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DDR2
Polyclonal
Unconjugated
Ddr2
AW495251; CD_antigen: CD167b; CD167 antigen-like family member B; CD167b; CD167b antigen; cell migration-inducing protein 20; Ddr2; Discoidin domain receptor 2; discoidin domain receptor family, member 2; discoidin domain receptor tyrosine kinase 2; discoidin domain-containing receptor 2; Discoidin domain-containing receptor tyrosine kinase 2; hydroxyaryl-protein; hydroxyaryl-protein kinase; MIG20a; migration-inducing gene 16 protein; neurotrophic tyrosine kinase receptor related 3; neurotrophic tyrosine kinase, receptor-related 3; Ntrkr3; receptor protein-tyrosine kinase TKT; RP11-572K18.1; TKT; TYRO10; tyrosine-protein kinase TYRO 10; tyrosine-protein kinase TYRO10; tyrosylprotein kinase
Rabbit
Antigen affinity chromatography
RUO
4921
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.05 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q16832
Ddr2
Recombinant Protein corresonding to Human DDR2. Recombinant protein control fragment (Product #RP-107731).
100 μL
Primary
Human
Antibody
IgG
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